DNA Structure
DNA stands for Deoxyribonucleic acid
DNA consists of two molecules that are arranged into a ladder-like structure called a Double Helix.
A molecule of DNA is made up of millions of tiny subunits called Nucleotides.
Each nucleotide consists of:
- Phosphate group
- Pentose sugar
- Nitrogenous base
Nucleotides
The phosphate and sugar form the backbone of the DNA molecule, whereas the bases form the “rungs”.
There are four types of nitrogenous bases.
- A - Adenine
- T - Thymine
- G - Guanine
- C - Cytosine
Each base will only bond with one other specific base.
Adenine (A)
Thymine (T)
Cytosine (C)
Guanine (G)
Base-Pair Rule
Adenine <==> Thymine
Guanine <==> Cytosine
The sides of the DNA ladder are phosphate & sugar held together by hydrogen bonds
DNA Structure
Because of this complementary base pairing, the order of the bases in one strand determines the order of the bases in the other strand.
G - C
G - C
A - T
T - A
T - A
A - T
A - T
C - G
T - A
G - C
C - G
A - T
T - A
C - G
Base Pair Rule
One side: A T A T C A T G C G G G
Other side:
DNA Structure
To crack the genetic code found in DNA we need to look at the sequence of bases.
The bases are arranged in triplets called codons.
A G G - C T C - A A G - T C C - T A G
T C C - G A G - T T C - A G G - A T C
DNA Structure
A gene is a section of DNA that codes for a protein.
Each unique gene has a unique sequence of bases.
This unique sequence of bases will code for the production of a unique protein.
It is these proteins and combination of proteins that give us a unique phenotype.
How the Code Works
The combination of A,T,G,C determines what traits you might have, for ex.
C A T C A T = purple hair
T A C T A C = yellow hair
Think of the bases of DNA like letters.
Letters form words....
Words form sentences....
*endless
combinations
Let's Review What We Know About DNA
1. DNA stands for: De _____ ribo ______ acid
2. What is the shape of DNA? _______________
3. Adenine always pairs with _______________
4. The sides of the DNA ladder are deoxyribose and _____
5. Guanine always pairs with _____________
6. What is the complementary sequence: A A T G C A
7. The two sides of DNA are held together by _______ bonds.
8. DNA is composed of repeating subunits called ______________________
9. What are the 4 bases that make up the rungs of the DNA ladder? _______________________________________
End